Advanced Concentration

Genetics

Mentor

Peter M. McGuire, Ph.D. 

Department

Biochemistry & Molecular Biology

Enrolled 

August 2003

Lab Room

CGRC Room 185

Lab Phone

273-8045

E-mail

kpause@ufl.edu

Education

B.S., Biological Science, Florida State University

Dissertation Research:  Conservation genetics of the Florida manatee

Florida manatees are one of the most widely recognized endangered species in the United States. Management and recovery efforts have been successful over the years in increasing manatee population sizes, but the genetic diversity of the species has been questioned. Previous studies with allozymes and mitochondrial DNA have demonstrated low genetic diversity, failing to resolve the specific population structure for Florida. Microsatellite libraries have been developed and screened to produce loci for population studies, pedigree analysis, and individual identification using a genetic fingerprint. These loci are being tested on the Florida population, and will be instrumental in confirming the genetic appropriateness of the established management units. A model DNA database for the Florida Manatee Genetic-identification System (MIGS) has been developed that will be integrated with the Florida Manatee Photo-identification System (MIPS) to complement population modeling based on mark-recapture methods.

Publications

Pause KC, Nourisson C, Clark AM, Kellogg ME, Bonde RK, McGuire PM. (2007) Polymorphic microsatellite DNA markers for the Florida manatee (Trichechus manatus latirostris). Molecular Ecology Notes.  (in press)

Pause KC, Bonde RK, McGuire PM, Zori RT, Gray BA.  G-banded karyotype and ideogram for the North Atlantic right whale (Eubalaena glacialis). J Hered. 2006 May-Jun;97(3):303-6.  abstract

Abstracts Presented at Meetings

Pause KC, Clark AM, Bonde RK, McGuire PM. A Preliminary Analysis of Gene Flow and Population Structure for the Florida manatee. 5-7 April 2006. Wildlife Society of Florida Spring Meeting, Cocoa Beach, FL. (presentation) 

Kellogg ME, Dennis TR, Gray BA, Duke DG, Pause KC, Bonde RK, Zori RT, McGuire PM. Molecular and Cytogenetic approaches to investigate the immune system of the endanagered Florida manatee (Trichechus manatus latirostris). 5-7 April 2006. Wildlife Society of Florida Spring Meeting, Cocoa Beach, FL. (poster) 

Pause KC, Clark AM, Bonde RK, McGuire PM. Genetic Studies of the Florida Manatee, Trichechus manatus latirostris. 10 December 2005. Sirenian International Symposium, San Diego, CA. (presentation) 

Pause KC, Bonde RK, McGuire PM, Zori R, Gray BA. December 2005. G-Banded Karyotype and Ideogram for the North Atlantic Right Whale (Eubalana glacialis), 16th Biennial Conference for the Society for Marine Mammalogy (poster) 

Nourisson C, Pause KC, Clark AM, Bonde RK, McGuire PM. December 2005. Development of Microsatellite DNA Markers for Genetic Studies for the Florida Manatee (Trichechus manatus latirostris), 16th Biennial Conference for the Society for Marine Mammalogy (poster) 

Kellogg ME, Gray BA, Duke DG, Pause KC, Bonde RK, McGuire PM. December 2005. Cytogenetic characterization, microdissection and cross-species fluorescence in situ hybridization (zoo-FISH) studies of the Florida manatee, Trichechus manatus latirostris, 16th Biennial Conference for the Society for Marine Mammalogy (poster) 

Pause KC, Nourisson C, Clark AM, Bonde RK, McGuire PM. Development of microsatellite DNA markers for genetic studies on the Florida manatee (Trichechus manatus latirostris). 30 November-1 December 2005. Florida Genetics Conference. Gainesville, FL. Pp. 15. (poster) 

Pause KC, Bonde RK, McGuire PM, Zori R, Gray BA (6 Apr 2005) G-Banded Karyotype and Ideogram for the North Atlantic Right Whale (Eubalana glacialis), Florida Marine Mammal Health Conference II (poster) 

Nourisson, C, Pause, K. C, Clark, A. M, Bonde, R. K, McGuire, P.M. (6 Apr 2005) Development of Microsatellite DNA Markers for Genetic Studies for the Florida Manatee (Trichechus manatus latirostris), Florida Marine Mammal Health Conference II (poster) 

Kellogg ME, Gray BA, Duke DG, Pause KC, Bonde RK, McGuire PM (2005) Techniques for establishing a cell culture and cytogenetic characterization of the Florida manatee, Trichechus manatus latirostris), Florida Marine Mammal Health Conference II (poster)

Honors & Awards

2005-2006, AAAS/Science Program for Excellence in Science, American Association for the Advancement of Science (AAAS), University of Florida