Melissa Marzahn


Advanced Concentration

Biochemistry and Molecular Biology

Mentor

Ben M. Dunn, Ph.D.

Department

Biochemistry & Molecular Biology

Enrolled 

August 2004

Lab Room

R3-191

Lab Phone

392-3367

E-mail

Melly13@ufl.edu

Education
B.S., Biochemistry, University of Texas, Arlington
Dissertation Research
Novel Plasmepsins from the Malaria Parasite Plasmodium falciparum
Publications

Peng Liu, Melissa R. Marzahn, Arthur Robbins, Hugo Gutiérrez de Teran , Johan Aqvist, Charles A. Yowell, Scott H. McClung, Stanley M. Stevens, Jr., John B. Dame and Ben M. Dunn. Recombinant plasmepsin 1 from human malaria parasite Plasmodium falciparum: Expression of an engineered variant with improved self cleavage, enzymatic characterization, combinatorial chemistry-based peptide inhibitor design, and crystal structure of PfPM2 with a peptidomimetic compound. In Preparation

Roxana M. Coman, C. Taylor Gilliland, Marty Fernandez, Melissa R. Marzahn, Maureen M. Goodenow, and Ben M. Dunn. Biochemical Studies of a Wide Range of HIV-1 Non-B Subtype Proteases.  In Preparation

Abstracts Presented at Meetings

Kristina Orrling, Melissa R. Marzahn, Hugo Gutierrez-de-Teranc, Johan Aqvistd, Ben M. Dunn, Mats Larhed. Investigation of the P1’ Substituent – Synthesis and Evaluation of Inhibitors of Malarial Aspartic Proteases.  1st International Conference on Drug Design and Discovery, Dubai, UAE, February 4-7, 2008.

Melissa R. Marzahn, Arati V. Majaraj, Raj P. Machhar, Zachary L. Johnson, Bret B. Beyer, Peng Liu, Roxana M. Coman, Ben M. Dunn. Characterization of Novel Drug Targets from the Malaria Parasite Plasmodium falciparum.  5th General Meeting of the International Proteolysis Society, Patras, Greece, October 20-24, 2007.

Ahu Demir, Roxana Coman, Melissa R. Marzahn, Ben M. Dunn. Purification, Characterization and New Inhibitor Approach of Human T-Cell Leukemia Virus-I Protease. 5th General Meeting of the International Proteolysis Society, Patras, Greece, October 20-24, 2007.

Melissa R. Marzahn, Peng Liu, Roxana M. Coman, Jose C. Clemente, Ben M. Dunn. Isolation and Characterization of Recombinant Aspartic Protease Plasmepsin 5 from the Plasmodium falciparum Malaria Parasite. 4th General Meeting of the International Proteolysis Society, Quebec City, Canada, October 15-19, 2005

Honors & Awards
Alumni Graduate Fellowship Award 2004-08

Current Students IDP Students IDP Home COM Home UF Home

last revised 6/25/08 tr