Brittney L. Gurda


Advanced Concentration

Biochemistry and Molecular Biology

Mentor

Mavis Agbandje-McKenna, Ph.D. 

Department

Biochemistry & Molecular Biology

Enrolled 

August 2005

Lab Room

LG-171

Lab Phone

846-2001

E-mail

bgurda@ufl.edu

Education

B.S., Microbiology & Cell Science, University of Florida

Dissertation Research

Mapping Dominant Antigenic Regions on Adeno-Associated Virus Capsids

Publications

Quesada O, Gurda B, Govindasamy L, McKenna R, Kohlbrenner E, Aslanidi G, Zolotukhin S, Muzyczka N, Agbandje-McKenna M.  Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7.  Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1073-6.  abstract

Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M.  Structure of Adeno-Associated virus serotype 8, a gene therapy vector. J Virol. 2007 Aug 29; [Epub ahead of print]  abstract

Grieger JC, Johnson JS, Gurda-Whitaker B, Agbandje-McKenna M, Samulski RJ.  Surface exposed Adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of non-infectious wild-type Vp2/Vp3 and Vp3-only capsids, but not 5-fold pore mutant virions. J Virol. 2007 Aug;81(15):7833-43.  abstract

Miller EB, Gurda-Whitaker B, Govindasamy L, McKenna R, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Related Articles, Links Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1271-4.  abstract

Nam HJ, Gurda-Whitaker B, Gan WY, Ilaria S, McKenna R, Mehta P, Alvarez RA, Agbandje-McKenna M.   Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation. J Biol Chem. 2006 Sep 1;281(35):25670-7.  abstract

DiMattia M, Govindasamy L, Levy HC, Gurda-Whitaker B, Kalina A, Kohlbrenner E, Chiorini JA, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M.  Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt 10):917-21. abstract

Lane MD, Nam HJ, Padron E, Gurda-Whitaker B, Kohlbrenner E, Aslanidi G, Byrne B, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M.  Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt 6):558-61. abstract

Abstracts Presented at Meetings

XIIth Parvovirus Workshop 2008, Cordoba, Spain. STRUCTURAL STUDIES OF BOCAVIRUSES: INSIGHTS INTO THE STRUCTURAL REPERTOIRE OF THE PARVOVORIDAE. Brittney L. Gurda, Heather Bladek, Alejandro Castro, Lakshamanan Govindasamy, Robert McKenna, Norm Olson, Robert Sinkovits, Tim S. Baker, Kevin Brown, Mavis Agbandje-McKenna.

XIIth Parvovirus Workshop 2008, Cordoba, Spain. STUDIES TOWARDS ENGINEERING IMMUNOEVASIVE AAV CAPSIDS FOR IMPROVED GENE THERAPY APPLICATIONS. Brittney L. Gurda, Michael DiMattia, Edward B.
Miller, Antonette Bennett, Robert McKenna, Sergei Zolotukhin, Weijun Chen, Nick Muzyczka, Wendy Weichert, Christian Nelson, Colin R. Parrish, Beverly Handelman, Jay Chiorini, Norm Olsen, Tim S. Baker, Mavis Agbandje-McKenna.

XXth Biennial Conference on Phage/Virus Assembly 2007. Barrie, Ontario, Canada. Mapping Dominant Antigenic regions on Adeno-Associated Virus Capsids. Brittney L. Gurda, Edward Miller, Michael DiMattia, Robert McKenna, Wendy Weichert, Christian Nelson, Colin R. Parrish, Sergei Zolotukhin, Michael Schmidt, Jay Chiorini, Norm Olson, Tim Baker, Mavis Agbandje-McKenna.

2007 Annual Meeting of the American Society for Virology. Corvallis, Oregon. Mapping Dominant Antigenic regions on Adeno-Associated Virus Capsids. Brittney L. Gurda, Edward Miller, Michael DiMattia, Robert McKenna, Wendy Weichert, Christian Nelson, Colin R. Parrish, Sergei Zolotukhin, Michael Schmidt, Jay Chiorini, Norm Olson, Tim Baker, Mavis Agbandje-McKenna.

XIth Parvovirus Workshop 2006, Les Diablerets, Switzerland. Mapping the Antigenic Site(s) of Neutralizing Antibodies on the Capsid of Adeno-Associated Virions. Brittney L. Gurda-Whitaker, Edward Miller, Michael DiMattia, Colin R. Parrish, Sergei Zolotukhin, Jay Chiorini, Robert McKenna, Mavis Agbandje-McKenna.

Honors & Awards
Howard Hughes Medical Institute Graduate Student Award, 2006


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last revised 6/16/08  tr