Catalog description: This course will
cover the design and use of gene transfer vectors for treating a variety of
diseases and will provide a practical understanding of the successes and hurdles
that are faced in gene therapy today with topics that are current.
Expanded description and explanation:
Evaluation of student performance:
Faculty: Dr.
Richard Snyder will be the course director. He will be assisted by faculty
from the College of Medicine who are experts in human genetics.
Summary of Topics:
Introductory Lecture and Viral vectors
Lecture # 1: Vectors: Viral and Non-Viral
Student review of 2 Papers
Lecture # 2: Gene Transfer Experiment Design
Student review of 2 Papers
Lecture # 3: Control of Vector Gene Expression
Student review of 2 Papers
Lecture # 4: Gene Therapy Applications : Cardiovascular
Student review of 2 Papers
Lecture # 5: Gene Therapy Applications : Inherited Monogenic Diseases
Student review of 2 Papers
Lecture # 6: Gene Theapy Applications : CNS
Student review of 2 Papers
Lecture # 7: Gene Transfer Experiments : Clinical
Student review of 2 Papers
Assigned readings: Reading assignments will included pertinent review articles and
original papers assigned by the faculty.
5-5-03 WTM