GMS 6036: Molecular Virology III - DNA Viruses


Catalog description:  Molecular biology and genetics of virology, focusing on the replication and pathogenesis of DNA viruses.

Pre-requisites: Consent of instructor

Expanded descriptions and explanation:   

This 5 week course will concentrate on the mechanisms by which DNA viruses replicate and interact with the host and cause disease. The viruses discussed will be: poxvirus (smallpox); papilloma virus (cervical carcinoma); herpesvirus; adenovirus and adeno-associated virus. The teaching format will involve lectures and paper discussions.

This course represents the second course in a 3-course sequence (GMS 6034, GMS 6036 and GMS 6035) dealing with the molecular biology and genetics of viruses, where the emphasis in this course is on the replication and pathogenesis of DNA viruses. The first course focuses on the genetics of viral systems, and the third course focuses on the reproduction of RNA viruses.

1. Papilloma virus I
2. Papilloma virus II
3. Papilloma virus III
4. Herpesvirus I
5. Herpesvirus II
6. Herpesvirus III
7. Herpesvirus IV
8. AAV I
9. AAV II
10. AAV III
11. Adenovirus I
12. Adenovirus II
13. Adenovirus III
14. Exam

Evaluation of student performance:  One final examination (80%), and oral discusssions (20%).

Faculty: Dr. Sue Moyer will be the course Director. She will be assisted in the presentation of material to the students by various Graduate Faculty of the College of Medicine.

Assigned Reading: The textbook for this course will be "Fundamental Virology", Fourth Edition, Knipe, D.M., and Howley, P.M. (Eds), (2001) Lippincott Williams & Wilkins, Philadelphia, PA. Additional readings will be assigned from the research literature.

10-29-02