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Physiology & Pharmacology Students |
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Physiology & Pharmacology Students |
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Physiology & Pharmacology |
Shuzhen Chen |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 1999 - May 2004 |
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Lab Room |
R5-281 |
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Lab Phone |
392-4076 |
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Education |
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Dissertation Research |
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TGF-b1
regulation of chemokine receptors in rat microglia and human macrophages |
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Publications |
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Davis CN, Chen S, Boehme SA, Bacon KB, Harrison JK. Chemokine receptor binding and signal transduction in native cells of the central nervous system. Methods. 2003 Apr;29(4):326-34. abstract |
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Chen S, Luo D, Streit WJ, Harrison JK. TGF-beta1 upregulates CX3CR1 expression and inhibits fractalkine-stimulated signaling in rat microglia. J Neuroimmunol. 2002 Dec;133(1-2):46-55. abstract |
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Harrison JK, Fong AM, Swain PA, Chen S, Yu YR, Salafranca MN, Greenleaf WB, Imai T, Patel DD. Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion. J Biol Chem. 2001 Jun 15;276(24):21632-41. abstract |
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Garcia GE, Xia Y, Chen S, Wang Y, Ye RD, Harrison JK, Bacon KB, Zerwes HG, Feng L. NF-kappaB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1beta, TNF-alpha, and LPS. J Leukoc Biol. 2000 Apr;67(4):577-84. abstract |
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Feng L, Chen S, Garcia GE, Xia Y, Siani MA, Botti P, Wilson CB, Harrison JK, Bacon KB. Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication. Kidney Int. 1999 Aug;56(2):612-20. abstract |
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Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, Streit WJ, Salafranca MN, Adhikari S, Thompson DA, Botti P, Bacon KB, Feng L. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10896-901. abstract |
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Chen S, Bacon KB, Li L, Garcia GE, Xia Y, Lo D, Thompson DA, Siani MA, Yamamoto T, Harrison JK, Feng L. In vivo inhibition of CC and CX3C chemokine-induced leukocyte infiltration and attenuation of glomerulonephritis in Wistar-Kyoto (WKY) rats by vMIP-II. J Exp Med. 1998 Jul 6;188(1):193-8. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Christopher N. Davis |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 1999 |
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Lab Room |
R5-281 |
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Lab Phone |
392-4076 |
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Education |
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B.S., University of Florida |
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Dissertation Research |
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Publications |
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Davis CN, Chen S, Boehme SA, Bacon KB, Harrison JK. Chemokine receptor binding and signal transduction in native cells of the central nervous system. Methods. 2003 Apr;29(4):326-34. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Ileana Montañez-Clemente Elder |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 2000 |
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Lab Room |
R5-175 |
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Lab Phone |
392-3228 |
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Education |
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B.S., Industrial Chemistry |
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Dissertation Research |
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Publications |
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An H, Tu C, Duda D, Montanez-Clemente I, Math K, Laipis PJ, McKenna R, Silverman DN. Chemical rescue in catalysis by human carbonic anhydrases II and III. Biochemistry. 2002 Mar 5;41(9):3235-42. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Michael D. Godeny |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Physiology & Functional Genomics |
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Enrolled |
August 2002 |
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Lab Room |
M-534 |
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Lab Phone |
392-1498 |
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Education |
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B.S., Biology, Pennsylvania State, University Park Campus |
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Dissertation Research |
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Publications |
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Sandberg EM, Ma X, VonDerLinden D, Godeny MD, Sayeski PP. Jak2 tyrosine kinase mediates angiotensin II-dependent inactivation of ERK2 via induction of mitogen-activated protein kinase phosphatase 1. J Biol Chem. 2004 Jan 16;279(3):1956-67. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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William B. Greenleaf |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 1999 - May 2004 |
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Lab Room |
R5-175 |
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Lab Phone |
392-3228 |
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Education |
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B.S., Florida State University |
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Dissertation Research |
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Proton
transfer in catalysis by iron and manganese superoxide dismutase |
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Publications |
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Hearn AS, Fan L, Lepock JR, Luba JP, Greenleaf WB, Cabelli DE, Tainer JA, Nick HS, Silverman DN. Amino-acid substitution at the dimeric interface of human manganese superoxide dismutase. J Biol Chem. 2003 Nov 24 abstract |
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Greenleaf WB, Silverman DN. Activation of the proton transfer pathway in catalysis by iron superoxide dismutase. J Biol Chem. 2002 Dec 20;277(51):49282-6. abstract |
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Harrison JK, Fong AM, Swain PA, Chen S, Yu YR, Salafranca MN, Greenleaf WB, Imai T, Patel DD. Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion. J Biol Chem. 2001 Jun 15;276(24):21632-41. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Renita Handayani |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 2000 |
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Lab Room |
R5-156 |
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Lab Phone |
392-3030 |
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Education |
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B.S., Pharmacy |
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Dissertation Research |
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Publications |
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Ason B, Handayani R, Williams CR, Bertram JG, Hingorani MM, O'Donnell M, Goodman MF, Bloom LB. Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. J Biol Chem. 2003 Mar 21;278(12):10033-40. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Susan LeFrancois |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 2000 |
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Lab Room |
R5-191 |
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Lab Phone |
392-0670 |
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Education |
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B.S., University of South Florida |
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Dissertation Research |
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Publications |
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Kem WR, Mahnir VM, Prokai L, Papke RL, Cao X, LeFrancois S, Wildeboer K, Prokai-Tatrai K, Porter-Papke J, Soti F. Hydroxy Metabolites of the Alzheimer's Drug Candidate 3-[(2,4-Dimethoxy)Benzylidene]-Anabaseine Dihydrochloride (GTS-21): Their Molecular Properties, Interactions with Brain Nicotinic Receptors, and Brain Penetration. Mol Pharmacol. 2004 Jan;65(1):56-67. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Michele L. Merves |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pathology, Immunology & Laboratory Science |
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Enrolled |
August 2001 |
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Lab Room |
Rocky Point Lab 1127 |
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Lab Phone |
265-9900 |
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Education |
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B.S., University of Cincinnati |
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Dissertation Research |
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Publications |
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Murray RA, Doering PL, Boothby LA, Merves ML, McCusker RR, Chronister CW, Goldberger BA. Putting an Ecstasy test kit to the test: harm reduction or harm induction? Pharmacotherapy. 2003 Oct;23(10):1238-44. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Beverly L. Metcalfe |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Physiology & Functional Genomics |
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Enrolled |
August 1999 - May 2004 |
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Lab Room |
L4-135 |
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Lab Phone |
392-9285 |
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Education |
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B.S., Microbiology, Bowling Green State University |
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Dissertation Research |
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Defining
the role of the angiotensin II type 2 receptor in cardiovascular disease |
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Publications |
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Coleman JE, Huentelman MJ, Kasparov S, Metcalfe BL, Paton JF, Katovich MJ, Semple-Rowland SL, Raizada MK. Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo. Physiol Genomics. 2003 Feb 6;12(3):221-8. abstract |
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Metcalfe BL, Sellers KW, Jeng MJ, Huentelman MJ, Katovich MJ, Raizada MK. Gene therapy for cardiovascular disorders: is there a future? Ann N Y Acad Sci. 2001 Dec;953:31-42. abstract |
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Metcalfe BL, Raizada M, Katovich MJ. Genetic targeting of the renin-angiotensin system for long-term control of hypertension. Curr Hypertens Rep. 2002 Feb;4(1):25-31. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Eric M. Sandberg |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 2000 |
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Lab Room |
M-535 |
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Lab Phone |
846-2081 |
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Education |
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B.S., Microbiology & Cell Science, University of Florida |
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Dissertation Research |
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Publications |
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Sandberg EM, Ma X, VonDerLinden D, Godeny MD, Sayeski PP. Jak2 tyrosine kinase mediates angiotensin II-dependent inactivation of ERK2 via induction of mitogen-activated protein kinase phosphatase 1. J Biol Chem. 2004 Jan 16;279(3):1956-67. abstract |
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VonDerLinden D, Ma X, Sandberg EM, Gernert K, Bernstein KE, Sayeski PP. Mutation of glutamic acid residue 1046 abolishes Jak2 tyrosine kinase activity. Mol Cell Biochem. 2002 Dec;241(1-2):87-94. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Kathleen W. Sellers |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Physiology & Functional Genomics |
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Enrolled |
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Lab Room |
L4-135 |
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Lab Phone |
392-9285 |
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Education |
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B.S., Biology, Winthrop University |
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Dissertation Research |
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Publications |
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Yang H, Francis SC, Sellers K, DeBarros M, Sun C, Sumners C, Ferrario CM, Katovich MJ, Muro AF, Raizada MK. Hypertension-linked decrease in the expression of brain gamma-adducin. Circ Res. 2002 Oct 4;91(7):633-9. abstract |
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Metcalfe BL, Sellers KW, Jeng MJ, Huentelman MJ, Katovich MJ, Raizada MK. Gene therapy for cardiovascular disorders: is there a future? Ann N Y Acad Sci. 2001 Dec;953:31-42. abstract |
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Sellers KW, Katovich MJ, Gelband CH, Raizada MK. Gene therapy to control hypertension: current studies and future perspectives. Am J Med Sci. 2001 Jul;322(1):1-6. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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Nilanjana Sengupta |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 2001 |
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Lab Room |
R5-244 |
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Lab Phone |
392-7958 |
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Education |
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B.S., Biology, University of South Carolina |
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Dissertation Research |
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Publications |
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Caballero S, Sengupta N, Crafoord S, Lund R, Kruse FE, Young M, Grant MB. The many possible roles of stem cells in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2004 Jan;242(1):85-90. abstract |
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Sengupta N, Caballero S, Mames RN, Butler JM, Scott EW, Grant MB. The role of adult bone marrow-derived stem cells in choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4908-13. abstract |
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Abstracts Presented at Meetings |
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Caballero S, Sengupta N, Mames RN, Scott EW, Grant MB. Stem cell recruitment and participation in choroidal neovascularization following rupture to Bruch’s membrane. Invest Ophthalmol Vis Sci 2003;44:ARVO Abstract 546. |
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Sengupta N, Caballero S, Scott EW, Mames RN, Guthrie, SM, Grant MB. Hemangioblast activity of stem cells as promoted by injury and modulated by nitric oxide in a model of retinal neovascularization. Invest Ophthalmol Vis Sci 2003;44:ARVO Abstract 2096. |
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Sengupta N, Caballero S, Mames RN, Scott EW, Grant MB. Preventing stem cell incorporation into aberrant ocular neovascularization. Keystone Symposia (Stem Cells), January 2004, Keystone, CO. Abstract 129. |
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Caballero S, Sengupta N, Mames RN, Scott EW, Grant MB. Hematopoietic stem cell contribution to rubeosis iridus. Keystone Symposia (Stem Cells), January 2004, Keystone, CO. Abstract 413. |
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Caballero S, Sengupta N, Mames RN, Scott EW, Grant MB. Hematopoietic Stem Cell Contribution to Neovascularization of the Iris. Invest Ophthalmol Vis Sci 2004;45:ARVO Abstract 502. |
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Sengupta N, Caballero S, Mames RN, Scott EW, Grant MB. Preventing Stem Cell Incorporation into Choroidal Neovascularization. Invest Ophthalmol Vis Sci 2004;45:ARVO Abstract 2233. |
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Honors & Awards |
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National Eye Institute Travel Grant ($700) to attend and present a paper at the Annual Meeting (2004) of the Association for Research in Vision and Ophthalmology (ARVO). |
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David G. Taylor |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 1999 |
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Lab Room |
R5-285 |
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Lab Phone |
392-5317 |
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Education |
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Dissertation Research |
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Publications |
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Taylor DG, Parilak LD, LeWinter MM, Knot HJ. Quantification of the rat left ventricle force and Ca(2+)-frequency relationships: similarities to dog and human. Cardiovasc Res. 2004 Jan 1;61(1):77-86. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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James K. Tolson |
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Advanced Concentration |
Physiology & Pharmacology |
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Mentor |
|||
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Department |
Pharmacology & Therapeutics |
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Enrolled |
August 1997 |
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Lab Room |
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Lab Phone |
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Education |
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B.S., Food Science, University of Florida |
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Dissertation Research |
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Publications |
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Halmes NC, Roberts SM, Tolson JK, Portier CJ. Reevaluating cancer risk estimates for short-term exposure scenarios. Toxicol Sci. 2000 Nov;58(1):32-42. abstract |
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Tolson JK, Moye HA, Toth JP. Effect of temperature and humidity on the formation of dibutylurea in benlate fungicide. J Agric Food Chem. 1999 Mar;47(3):1217-22. abstract |
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Abstracts Presented at Meetings |
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Honors & Awards |
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