|
Genetics Alumni |
|
|
Genetics |
| Amelio | Andino | Bongorno | Bray | Charron | |||
| Collins | Conlon | Cresawn K | Cresawn S | Dong | Eckenrode | ||
| Fritz | Kaplan | Khalil | Kiefer | Latner | |||
| Marshall | McAuliffe | Muller | Nykamp | Pacak | |||
| Rucker-Schleissing | Walrath | White |
Antonio Amelio, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - December 2005 |
|
|
Dissertation Title |
Factors involved in epigenetic regulation of the HSV-1 reactivation critical region (rcr) during latency and reactivation |
|
|
Professional Positions |
||
|
Education |
||
|
M.S., Business Administration - Concentration Management, University of Florida, 2004 |
||
|
B.S. (Summa Cum Laude) Microbiology & Cell Science, Univeristy of Florida, 2000 |
||
|
Publications |
||
|
Amelio AL, McAnany PK, Bloom DC. CTCF Binds to Several Clusters of CTCF Consensus Motifs within the HSV-1 Genome during Latency. J Virol Submitted |
||
|
Kubat NJ, Amelio AL, Giordani NV, Bloom DC. The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independent of Lat Transcription. J Virol 78:12508-12518 abstract |
||
|
Abstracts Presented at Meetings during Graduate Studies |
||
|
30th International Herpes Virus Workshop, Turku, Finland. July 2005. Amelio AL, Bloom DC. Identification of a Chromatin Insulator with Enhancer-Blocking Activity Located within the HSV-1 LAT region. Poster/Oral |
||
|
24th Annual American Society for Virology Meeting, Penn State Univ, PA. June 2005. Amelio AL, Bloom DC. Characterization of a cell-type specific transcriptional boundary in the HSV-1 LAT locus. Oral. |
||
|
2nd Annual Florida TechTransfer Conference, Orlando, FL. May 2005. Amelio, Bloom DC. Insulated Herpesvirus-Derived Expression Cassette and Insulated Viral Artificial Chromosome (IVAC) for Sustained and Regulatable Gene Delivery to the Nervous System. Poster. |
||
|
29th Internation Herpesvirus Workshop, Reno, NV. 2004. Amelio AL, Jubat NJ, Giordani NV, Bloom DC. Transcription of the LAT is not required to maintain hyperacetylation of the region encoding the LAT 5' exon. Poster. |
||
|
36th Annual Student Science Training Program Research Presentation, Gainesville, FL. 1994. Amelio AL, Welt B, Teixieira AA. The effects of Pre-Irradiation on the thermal resistance of Bacillus stearothermophilus spores. |
||
|
Honors & Awards |
||
|
Gold Medal Finalist, Medical Guild Graduate Student Research Competition, 2005 |
||
|
First Place, Genetics Advanced Concentration, Medical Guild Graduate Student Research Concentration, 2005 |
||
|
President of the College of Medicine Graduate Organization, 2001-2002 |
||
|
UF President's Honor Roll, 1999 |
||
|
Golden Key National Honor Society, 1999 |
||
|
Alpha Zeta Professional Fraternity, 1999 |
||
|
Hazel N. Crews Academic Scholarship, 1998-1999 |
||
|
College Student of the Year, Indian River Community College 1997-1998 |
||
|
Donald C. Hicks Memorial "Stars" Academic Scholarship, 1996-1998 |
||
|
Phi Theta Kappa National Honor Society, 1996-1998 |
||
Lourdes M. Andino, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - August 2006 |
|
|
Dissertation Title |
Repressing a repressor: Adeno-associated virus delivered short hairpin RNA molecules targeting phospholamban | |
|
Professional Positions |
||
|
Education |
||
| B.S., Biochemistry, Florida International University | ||
|
Publications |
||
| Szmulewicz MN, Andino LM, Reategui EP, Woolley-Barker T, Jolly CJ, Disotell TR, Herrera RJ. An Alu insertion polymorphism in a baboon hybrid zone. Am J Phys Anthropol. 1999 May;109(1):1-8. abstract | ||
|
Abstracts Presented at Meetings during Graduate Studies |
||
|
|
||
|
Honors & Awards |
||
Christopher Bray, (M.D., Ph.D.) |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - August 2005 (Ph.D. portion of M.D./Ph.D. program) |
|
|
Dissertation Title |
Hemangioblastic origins of the adult endothelial progenitor cell (PDF) | |
|
Professional Positions |
||
|
Medical Student, UF College of Medicine |
||
|
Education |
||
|
B.S., Florida State University |
||
|
Publications |
||
| Fisher RC, Slayton WB, Chien C, Guthrie SM, Bray C, Scott EW. PU.1 supports proliferation of immature erythroid progenitors. Leuk Res. 2004 Jan;28(1):83-9. abstract | ||
Lauren Morges Brum, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1998 - May 2003 |
|
|
Dissertation Title |
Characterization of the poxvirus serpins SPI-1 and SPI-3 (full-text) |
|
|
Professional Positions |
||
|
Postdoctoral Associate, University of Florida College of Pharmacy |
||
|
Education |
||
|
Publications |
||
|
Brum LM, Lopez MC, Varela JC, Baker HV, Moyer RW. Microarray analysis of A549 cells infected with rabbitpox virus (RPV): a comparison of wild-type RPV and RPV deleted for the host range gene, SPI-1. Virology. 2003 Oct 25;315(2):322-34. abstract |
||
|
Brum LM, Turner PC, Devick H, Baquero MT, Moyer RW. P lasma membrane localization and fusion inhibitory activity of the cowpox virus serpin SPI-3 require a functional signal sequence and the virus encoded hemagglutinin. Virology. 2003 Feb 15;306(2):289-302. abstract |
||
Kevin S. Cahill (M.D./Ph.D.) |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - December 2003 |
|
|
Dissertation Title |
Enhancement of stem-cell transplantation strategies for muscle regeneration (full text) |
|
|
Professional Positions |
||
|
Medical Student, University of Florida College of Medicine (MD/Ph.D. program) |
||
|
Education |
||
|
BS, University of Florida, 1999 |
||
|
Publications |
||
|
Cahill KS, Toma C, Pittenger MF, Kessler PD, Byrne BJ. Cell therapy in the heart: cell production, transplantation, and applications. Methods Mol Biol. 2003;219:73-81. abstract |
||
|
Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation. 2002 Jan 1;105(1):93-8. abstract |
||
Stormy J. Chamberlain, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
Camilynn I. Brannan, Ph.D. & James L. Resnick, Ph.D. |
|
|
Department |
||
|
Enrolled |
August 1997 - May 2003 |
|
|
Dissertation Title |
Elucidation of imprinting mechanisms and phenotypes in Prader-Willi syndrome mice |
|
|
Professional Positions |
||
|
Postdoctoral Associate, Dept. of Genetics, University of North Carolina, Chapel Hill, NC |
||
|
Education |
||
|
B.A., Molecular Biology, Princeton University, Princeton, NJ |
||
|
Publications |
||
|
Chamberlain SJ, Brannan CI. The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a. Genomics. 2001 May 1;73(3):316-22. abstract |
||
|
Vanrheenen SM, Reilly BA, Chamberlain SJ, Waters MG. Dsl1p, an essential protein required for membrane traffic at the endoplasmic reticulum/Golgi interface in yeast. Traffic. 2001 Mar;2(3):212-31. abstract |
||
|
Lee S, Kozlov S, Hernandez L, Chamberlain SJ, Brannan CI, Stewart CL, Wevrick R. Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype. Hum Mol Genet. 2000 Jul 22;9(12):1813-9. abstract |
||
|
Honors & Awards |
||
|
Medical Guild Graduate Student Research Competition, First Place Genetics, First Place Overall, 2003 |
||
Catherine E. Charron, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2001 - August 2005 |
|
|
Dissertation Title |
Gene Therapy for Phenylketonuria: Dominant-negative Interference in a Recessive Disease (PDF) | |
|
Professional Positions |
||
| Postdoctoral Research Associate, National Heart & Lung Institute, Imperial College, London | ||
|
Education |
||
| B.S., Chemistry, University of Florida | ||
|
Publications |
||
Christin Collins, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
Jin-Xiong She, Ph.D. |
|
|
Department |
||
|
Enrolled |
August 1999 - May 2005 |
|
| Dissertation Title | Gene expression profiling of peripheral blood lymphocytes from type 1 diabetes patients | |
|
Professional Positions |
||
|
Postdoctoral Associate, Center for Biotechnology & Genomic Medicine, Medical College of Georgia, Augusta, GA |
||
|
Publications |
||
|
Eckenrode SE, Ruan QG, Collins CD, Yang P, McIndoe RA, Muir A, She JX. Molecular pathways altered by insulin b9-23 immunization. Ann N Y Acad Sci. 2004 Dec;1037:175-85. abstract |
||
|
Yang L, Zhao H, Li SW, Ahrens K, Collins C, Eckenrode S, Ruan QG, McIndoe RA, She JX. Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells. J Mol Diagn. 2003 Nov;5(4):212-21. abstract |
||
|
Zhu H, Zhao H, Collins CD, Eckenrode SE, Ruan Q, McIndoe RA, Crawford JM, Nelson DR, She JX, Liu C. Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line. Hepatology. 2003 May;37(5):1180-8. abstract |
||
Thomas J. Conlon, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
|
|
|
Dissertation Title |
Hepatocyte transduction by recombinant adeno-associated virus as an approach to gene therapy for alpha-1 antitrypsin deficiency and fatty acid oxidation disorders |
|
|
Professional Positions |
||
|
Education |
||
|
|
||
|
Publications |
||
|
Conlon TJ, Flotte TR. Recombinant adeno-associated virus vectors for gene therapy. Expert Opin Biol Ther. 2004 Jul;4(7):1093-101. abstract |
||
|
Loiler SA, Conlon TJ, Song S, Tang Q, Warrington KH, Agarwal A, Kapturczak M, Li C, Ricordi C, Atkinson MA, Muzyczka N, Flotte TR. Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver. Gene Ther. 2003 Sep;10(18):1551-8. abstract |
||
|
Owen R 4th, Mandel RJ, Ammini CV, Conlon TJ, Kerr DS, Stacpoole PW, Flotte TR. Gene therapy for pyruvate dehydrogenase E1alpha deficiency using recombinant adeno-associated virus 2 (rAAV2) vectors. Mol Ther. 2002 Sep;6(3):394-9. abstract |
||
|
Wu P, Xiao W, Conlon T, Hughes J, Agbandje-McKenna M, Ferkol T, Flotte T, Muzyczka N. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. J Virol. 2000 Sep;74(18):8635-47. abstract |
||
Kerry O. Cresawn, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1998 - May 2004 |
|
|
Dissertation Title |
Liver-directed strategies and immunologic consequences of recombinant AAV-mediated cross-correction of glycogen storage disease type II |
|
|
Professional Positions |
||
|
Postdoctoral Associate (lab of Dr. Barry Byrne), Department of Pediatrics, UF College of Medcine |
||
|
Education |
||
|
B.S., James Madison University, Harrisonburg, VA |
||
|
Publications |
||
|
Mah C, Fraites TJ Jr, Cresawn KO, Zolotukhin I, Lewis MA, Byrne BJ. A new method for recombinant adeno-associated virus vector delivery to murine diaphragm. Mol Ther. 2004 Mar;9(3):458-63. abstract |
||
|
Abstracts Presented at Meetings During Graduate Studies |
||
|
Cresawn,KO, Porvasnik,SL, Raben,R, Plotz, PR and BJ Byrne. Inhibition of Humoral Immunity in Liver-Targeted Gene Therapy for Glycogen Storage Disease Type II. American Society of Gene Therapy 5th Annual Meeting, June 5-9, 2002. Molecular Ther., Vol 5, (5) Part 2 of 2; S342, May 2002. |
||
Steven Cresawn, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1999 - April 2005 |
|
|
Education |
||
|
B.S., Chemistry, University of Florida |
||
| Professional Position | ||
| Postdoctoral Fellow, UF, College of Medicine | ||
|
Dissertation Research |
||
|
Publications |
||
|
Prins C, Cresawn SG, Condit RC. An isatin-beta-thiosemicarbazone-resistant vaccinia virus containing a mutation in the second largest subunit of the viral RNA polymerase is defective in transcription elongation. J Biol Chem. 2004 Oct 22;279(43):44858-71. Epub 2004 Aug 3. abstract |
||
|
Abstracts Presented at Meetings during Graduate Studies |
||
|
Honors & Awards |
||
Hui-Jia Dong, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - April 2005 |
|
|
Education |
||
|
B.S., Microbiology |
||
| Professional Position Postdoctoral Fellow, UF, College of Medicine | ||
|
Dissertation Research |
||
|
Epigenetic modifications in the Angelman and Prader-Willi region of chromosome 15 |
||
|
Publications |
||
|
Lossie AC, Whitney MM, Amidon D, Dong HJ, Chen P, Theriaque D, Hutson A, Nicholls RD, Zori RT, Williams CA, Driscoll DJ. Distinct phenotypes distinguish the molecular classes of Angelman syndrome. J Med Genet. 2001 Dec;38(12):834-45. abstract |
||
Sarah E. Eckenrode, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
Jin-Xiong She, Ph.D. |
|
|
Department |
||
|
Enrolled |
Augst 1997 - August 2002 |
|
|
Dissertation Title |
Characterization of the molecular basis of type 1 diabetes using linkage and microarray analysis (full-text) |
|
|
Professional Positions |
||
|
Postdoctoral Associate, Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA |
||
|
Education |
||
|
BA, Lebanon Valley College, Annville, PA |
||
|
Publications |
||
|
Eckenrode SE, Ruan Q, Yang P, Zheng W, McIndoe RA, She JX. Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice. Diabetes. 2004 Feb;53(2):366-75. abstract |
||
|
Yang L, Zhao H, Li SW, Ahrens K, Collins C, Eckenrode S, Ruan QG, McIndoe RA, She JX. Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells. J Mol Diagn. 2003 Nov;5(4):212-21. abstract |
||
|
Wilson KH, Eckenrode SE, Li QZ, Ruan QG, Yang P, Shi JD, Davoodi-Semiromi A, McIndoe RA, Croker BP, She JX. Microarray analysis of gene expression in the kidneys of new- and post-onset diabetic NOD mice. Diabetes. 2003 Aug;52(8):2151-9. abstract |
||
|
Zhu H, Zhao H, Collins CD, Eckenrode SE, Ruan Q, McIndoe RA, Crawford JM, Nelson DR, She JX, Liu C. Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line. Hepatology. 2003 May;37(5):1180-8. abstract |
||
|
Kukar T, Eckenrode S, Gu Y, Lian W, Megginson M, She JX, Wu D. Protein microarrays to detect protein-protein interactions using red and green fluorescent proteins. Anal Biochem. 2002 Jul 1;306(1):50-4. abstract |
||
|
Li QZ, Eckenrode S, Ruan QG, Wang CY, Shi JD, McIndoe RA, She JX. Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age. Mamm Genome. 2001 Nov;12(11):830-6. abstract |
||
|
Yang MC, Ruan QG, Yang JJ, Eckenrode S, Wu S, McIndoe RA, She JX. A statistical method for flagging weak spots improves normalization and ratio estimates in microarrays. Physiol Genomics. 2001 Oct 10;7(1):45-53. abstract |
||
|
Li QZ, Wang CY, Shi JD, Ruan QG, Eckenrode S, Davoodi-Semiromi A, Kukar T, Gu Y, Lian W, Wu D, She JX. Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily. Gene. 2001 Aug 8;273(2):275-84. abstract |
||
|
Eckenrode S, Marron MP, Nicholls R, Yang MC, Yang JJ, Guida Fonseca LC, She JX. Fine-mapping of the type 1 diabetes locus (IDDM4) on chromosome 11q and evaluation of two candidate genes (FADD and GALN) by affected sibpair and linkage-disequilibrium analyses. Hum Genet. 2000 Jan;106(1):14-8. abstract |
||
|
Marron MP, Zeidler A, Raffel LJ, Eckenrode SE, Yang JJ, Hopkins DI, Garchon HJ, Jacob CO, Serrano-Rios M, Martinez Larrad MT, Park Y, Bach JF, Rotter JI, Yang MC, She JX. Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33. Diabetes. 2000 Mar;49(3):492-9. abstract |
||
|
Reimsnider SK, Eckenrode SE, Marron MP, Muir A, She JX. IL4 and IL4Ralpha genes are not linked or associated with type 1 diabetes. Pediatr Res. 2000 Feb;47(2):246-9. abstract |
||
Lauren Fishbein (M.D./Ph.D.) |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1999 - August 2004 (M.D./Ph.D. program) |
|
|
Dissertation Title |
|
|
|
Professional Positions |
||
|
Medical Student, University of Florida College of Medicine (M.D./Ph.D. program) |
||
|
Education |
||
|
B.A., Biochemistry, Vassar College, NY |
||
|
Publications |
||
|
Fishbein L, Eady B, Sanek N, Muir D, Wallace MR. Analysis of somatic NF1 promoter methylation in plexiform neurofibromas and Schwann cells. 2004 Cancer Genetics and Cytogenetics. (in press) |
||
|
Thomson SA, Fishbein L, Wallace MR. NF1 mutations and molecular testing. J Child Neurol. 2002 Aug;17(8):555-61; discussion 571-2, 646-51. Review. abstract |
||
|
Fishbein L, O'Brien P, Hutson A, Theriaque D, Stacpoole PW, Flotte T. Pharmacokinetics and pharmacodynamic effects of nicotine nasal spray devices on cardiovascular and pulmonary function. J Investig Med. 2000 Nov;48(6):435-40. abstract |
||
|
Hutson AD, Fishbein L, O'Brien P, Stacpoole PW. Accounting for plasma levels below detection limits in a one-compartment zeroorder absorption pharmacokinetics model. J Applied Statistics. 2000 29(8): 1181-1190. |
||
|
Pokrywka NJ, Fishbein L, Frederick J. New phenotypes associated with the swallow gene of Drosophila: evidence for a general role in oocyte cytoskeletal organization. Dev Genes Evol. 2000 Sep;210(8-9):426-35. abstract |
||
|
Honors & Awards |
||
|
NRSA from NINDS for predoctoral MD/PhD fellows, Aug 2002 - Aug 2007 |
||
|
National Cancer Institute Cancer Biology Training Grant, Oct 2001 - July 2002 |
||
|
American Society of Human Genetics, Member ,1999-present |
||
|
The American Federation of Medical Research (AFMR) Student Travel Grant Award to the Experimental Biology Conference in Washington, DC, 1999 |
||
|
University of Florida Medical Student Summer Research Grant, 1998 |
||
|
American Medical Women's Association, Member, 1997-1999 |
||
|
The Olive M. Lammert Prize for Excellence in the Study of Biochemistry |
||
|
Vassar College Departmental Honors in Biochemistry, 1997 |
||
|
Vassar College General Honors, 1997 |
||
|
Eating Disorder Reachout Service, Vassar College, 1994-1997. President 1996-97, Secretary 1995-96. |
||
|
The Listening Center Peer Counseling, Vassar College 1994-1997. President 1996-97, Counselor trainer. |
||
Thomas J. Fraites, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - December 2003 |
|
|
Dissertation Title |
Muscle-directed gene and enzyme replacement therapies for glycogen storage disorder type II, Pompe disease |
|
|
Professional Positions |
||
|
Postdoctoral Associate (lab of Dr. Barry Byrne), Dept. Pediatrics, UF College of Medcine |
||
|
Education |
||
|
B.S., Biomedical Engineering, Johns Hopkins University, Baltimore, MD |
||
|
M.S., Medical Sciences, M.B.A., University of Florida |
||
|
Publications |
||
|
Zolotukhin S, Potter M, Zolotukhin I, Sakai Y, Loiler S, Fraites TJ Jr, Chiodo VA, Phillipsberg T, Muzyczka N, Hauswirth WW, Flotte TR, Byrne BJ, Snyder RO. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods. 2002 Oct;28(2):158-67. abstract |
||
|
Mah C, Fraites TJ Jr, Zolotukhin I, Song S, Flotte TR, Dobson J, Batich C, Byrne BJ. Improved method of recombinant AAV2 delivery for systemic targeted gene therapy. Mol Ther. 2002 Jul;6(1):106-12. abstract |
||
|
Fraites TJ Jr, Schleissing MR, Shanely RA, Walter GA, Cloutier DA, Zolotukhin I, Pauly DF, Raben N, Plotz PH, Powers SK, Kessler PD, Byrne BJ. Correction of the enzymatic and functional deficits in a model of Pompe disease using adeno-associated virus vectors. Mol Ther. 2002 May;5(5 Pt 1):571-8. abstract |
||
|
Pauly DF, Fraites TJ, Toma C, Bayes HS, Huie ML, Hirschhorn R, Plotz PH, Raben N, Kessler PD, Byrne BJ. Intercellular transfer of the virally derived precursor form of acid alpha-glucosidase corrects the enzyme deficiency in inherited cardioskeletal myopathy Pompe disease. Hum Gene Ther. 2001 Mar 20;12(5):527-38. abstract |
||
|
Fraites TJ Jr, Saeki A, Kass DA. Effect of altering filling pattern on diastolic pressure-volume curve. Circulation. 1997 Dec 16;96(12):4408-14. abstract |
||
|
Honors & Awards |
||
|
National Merit Scholar, Johns Hopkins University, 1992 |
||
|
Provost's Undergraduate Award for Research and Excellence, Johns Hopkins University, 1995 |
||
|
American Society of Gene Therapy, Student Award for Excellence in Research, 2000 |
||
|
Beta Gamma Sigma, University of Florida, 2000 |
||
|
Poe/Southern Family Business Ethics Fellow, University of Florida, 2000 |
||
|
Linton E. Grinter Graduate School Fellowship, University of Florida, 2000 |
||
|
American Heart Association, Florida/Puerto Rico Affiliate, 2000-2002 |
||
Jason J. Fritz, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1997 - August 2004 |
|
|
Dissertation Title |
|
|
|
Professional Positions |
||
|
Postdoctoral Associate, Center for Neurodegenrative Disease, Emory University, Atlanta, GA |
||
|
Education |
||
|
B.S., Microbiology, University of South Florida |
||
|
Publications |
||
|
Fritz JJ, Lewin A, Hauswirth W, Agarwal A, Grant M, Shaw L. Development of hammerhead ribozymes to modulate endogenous gene expression for functional studies. Methods. 2002 Oct;28(2):276-85. abstract |
||
|
Fritz JJ, White DA, Lewin AS, Hauswirth WW. Designing and characterizing hammerhead ribozymes for use in AAV vector-mediated retinal gene therapies. Methods Enzymol. 2002;346:358-77. abstract |
||
Rahul N. Kanadia, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 1999 - May 2004 |
|
|
Dissertation Title |
Involvement
of muscleblind proteins in pathogenesis of myotonic dystrophy |
|
|
Professional Positions |
||
|
Postdoctoral Associate (lab of Dr. Maurice Swanson), Dept. Molecular Genetics & Microbiology, UF College of Medcine |
||
|
Education |
||
|
B.S., Bethune-Cookman College, Daytona Beach, FL |
||
|
Publications |
||
|
Kanadia RN, Johnstone KA, Mankodi A, Lungu C, Thornton CA, Esson D, Timmers AM, Hauswirth WW, Swanson MS. A muscleblind knockout model for myotonic dystrophy. Science. 2003 Dec 12;302(5652):1978-80. abstract |
||
|
Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS. Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62. abstract |
||
|
Kuo WN, Kanadia RN, Shanbhag VP, Toro R. Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart. Mol Cell Biochem. 1999 Nov;201(1-2):11-6. abstract |
||
|
Kuo WN, Kanadia RN, Shanbhag VP, Morgan R. Modification of proteins and polynucleotides by peroxynitrite. Cytobios. 1999;99(390):47-55. abstract |
||
|
Kuo WN, Kanadia RN, Shanbhag VP. Denitration of peroxynitrite-treated proteins by "protein nitratases" from dog prostate. Biochem Mol Biol Int. 1999 Jun;47(6):1061-7. abstract |
||
|
Kanadia RN, Kuo WN, Mcnabb M, Botchway A. Constitutive nitric oxide synthase in Saccharomyces cerevisiae. Biochem Mol Biol Int. 1998 Sep;45(6):1081-7. abstract |
||
|
Kuo WN, Kanadia RN, Mcnabb M. Soluble guanylate cyclase in Saccharomyces cerevisiae. Biochem Mol Biol Int. 1998 Jun;45(1):125-31. abstract |
||
|
Kuo WN, McNabb M, Kanadia RN, Dopson N, Morgan R. The presence/absence of Bcl-2, Ca2+/calmodulin-dependent protein kinase IV, calretinin and p53 in baker's yeast and wheat germ. Cytobios. 1997;91(364):7-13. abstract |
||
|
Kuo WN, Jn-Baptiste JB, Zhai L, Chambers MC, Kanadia R. Immunoreactivities of p11 and calcyclin in baker's yeast, wheat germ and lobster. Biochem Mol Biol Int. 1997 Jan;41(1):209-15. abstract |
||
|
Kuo WN, Jn-Baptiste JB, Kanadia RN, McNabb LD, Zhai L, Weeks K, Dopson N, Chambers MC. Immunoreactivities of m-calpain, calpastatin, nitric oxide synthase, myelin basic protein and dynamin II in baker's yeast, wheat germ and lobster tail muscle. Cytobios. 1996;87(351):251-63. abstract |
||
|
Honors & Awards |
||
|
Medical Guild Graduate Student Research Competition, First Place in Genetics, Second Place Overall, 2004 |
||
|
Graduate Fellowship for Outstanding Reseach, UF College of Medicine, 2003 |
||
Lee Kaplan, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
Margaret R. Wallace, Ph.D. | |
|
Department |
Molecular Genetics & Microbiology | |
|
Enrolled |
August 2001 - December 2005 |
|
|
Dissertation Title |
Elucidating the genetic influences in pain sensitivity and analgesic effect | |
|
Professional Positions |
||
|
Education B.S., Psychology and Genetics, University of Stellenbosch (South Africa) |
||
|
Publications |
||
|
Zhang J, Kumar A, Kaplan L, Fricker FJ, Wallace MR. Genetic linkage of a novel autosomal dominant restrictive cardiomyopathy locus. J Med Genet. 2005 Aug;42(8):663-5. abstract |
||
|
Mogil JS, Ritchie J, Smith SB, Strasburg K, Kaplan L, Wallace MR, Romberg RR, Bijl H, Sarton EY, Fillingim RB, Dahan A. Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. J Med Genet. 2005 Jul;42(7):583-7. abstract |
||
|
Fillingim RB, Kaplan L, Staud R, Ness TJ, Glover TL, Campbell CM, Mogil JS, Wallace MR. The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain. 2005 Mar;6(3):159-67. abstract |
||
|
Hill-Harfe KL, Kaplan L, Stalker HJ, Zori RT, Pop R, Scherer G, Wallace MR. Fine Mapping of Chromosome 17 Translocation Breakpoints >/=900 Kb Upstream of SOX9 in Acampomelic Campomelic Dysplasia and a Mild, Familial Skeletal Dysplasia. Am J Hum Genet. 2005 Feb 16;76(4) [Epub ahead of print] abstract |
||
|
Mogil JS, Wilson SG, Chesler EJ, Rankin AL, Nemmani KV, Lariviere WR, Groce MK, Wallace MR, Kaplan L, Staud R, Ness TJ, Glover TL, Stankova M, Mayorov A, Hruby VJ, Grisel JE, Fillingim RB. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci USA. 2003 Apr 15;100(8):4867-72. abstract |
||
|
Stalker H, Zori R, Wallace M, Hill-Harfe K, Kaplan L. Reply to Unger: The mildest form of campomelic dysplasia. Am J Med Genet A. 2005 Jan 1;132A(1):114-5. |
||
|
Metcalf T, Kelley K, Erdos GW, Kaplan L, West CM. Formation of the outer layer of the Dictyostelium spore coat depends on the inner-layer protein SP85/PsB. Microbiology. 2003 Feb;149(Pt 2):305-17. abstract |
||
|
West CM, Zhang P, McGlynn AC, Kaplan L. Outside-in signaling of cellulose synthesis by a spore coat protein in Dictyostelium. Eukaryot Cell. 2002 Apr;1(2):281-92. abstract |
||
|
Van Der Wel H, Morris HR, Panico M, Paxton T, Dell A, Kaplan L, West CM. Molecular cloning and expression of a UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase that modifies Skp1 in the cytoplasm of dictyostelium. J Biol Chem. 2002 Nov 29;277(48):46328-37. abstract |
||
|
Abstracts Presented at Meetings during Graduate Studies |
||
|
Hill-Harfe, Katherine, Lee Kaplan, Heather Stalker, Roberto Zori, Margaret Wallace. Molecular Analysis of a Translocation Breakpoint in a Family with Dominant Skeletal Dysplasia: Toward a Novel Gene/Mechanism. American College of Medical Genetics Annual Clinical Genetics Meeting, 2004, Orlando Florida. (Poster jointly presented with Dr. Hill-Harfe). |
||
|
Kaplan, L, R. Fillingim, M. Agbandje-McKenna, R. Staud, T. Glover, C. Campbell, J. Mogil, M. Wallace. Functional Effects of the t80g snp of the delta opioid Receptor in Baseline Pain Sensitivity. The 2nd Joint Scientific Meeting of the American Pain Society and the Canadian Pain Society 2004, Vancouver, BC. |
||
|
Fillingim, R., L. Kaplan, R. Staud, T. Ness, T. Glover, C. Campbell, J. Mogil, M. Wallace The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. The 2nd Joint Scientific Meeting of the American Pain Society and the Canadian Pain Society, 2004,Vancouver, BC. |
||
| Honors & Awards | ||
| 2005 UF President's Award | ||
|
2003-04 President, University of Florida College of Medicine Graduate Student Organization |
||
|
2003-present Member of the American Pain Society |
||
|
2002-present Member of the American Society of Human Genetics |
||
|
2002-03 Vice President, Univ. Florida College of Medicine Graduate Student Organization |
||
Ahmad M. Khalil, Ph.D. |
||
|
Advanced Concentration |
||
|
Mentor |
||
|
Department |
||
|
Enrolled |
August 2000 - December 2004 |
|
|
Dissertation Title |
Histone modifications and chromatin dynamics of the mammalian inactive sex chromosomes |
|
| Web Page | http://myprofile.cos.com/AhmadK78 | |
|
Professional Positions |
||
|
Postdoctoral Associate, Pediatric Genetics, Center for Mammalian Genetics, The Genetics Institute, UF College of Medicine |
||
|
Education |
||
|
B.A., Biology, University of Kansas |
||
|
Publications |
||
|
Khalil AM, and Driscoll DJ. Histone H3 lysine 4 dimethylation is enriched on the inactive sex chromosomes in male meiosis but absent on the inactive X in female somatic cells. Cytogenet Genome Res 2006;112 (in press) |
||
|
Khalil AM, Boyar FZ, Driscoll DJ. Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis. Proc Natl Acad Sci U S A. 2004 Nov 9;101:16583-16587. abstract |
||
|
Khalil AM, Driscoll DJ. Tri-methylation of Histone H3 Lysine 4 is an Epigenetic Mark for Regions Escaping X Inactivation. (in preparation) |
||
|
Khalil AM, Driscoll DJ. Histone 3 Lysine 4 Dimethylation is Enriched on the Inactive X in Male Meiosis but Absent on the Inactive X in Females. (in preparation) |
||
|
Honors & Awards |
||
|
Postdoctoral Award, Keystone Symposia: Epigenetics and Chromatin Remodeling in Development, Keystone, CO, January 2006 Finalist, Postdoctoral Basic Science Outstanding Research Award, American Society of Human Genetics, Salt Lake City, UT, October 26-30, 2005 (Note: three finalists are selected each year) Platform Presentation, American Society of Human Genetics, Salt Lake City, UT, October 25-29, 2005 2005 NRSA Postdoctoral Fellowship, National Institute of Health (NIH) and the University of Florida College of Medicine Postdoctoral Award, Keystone Symposia - Chromatin Modification Pathways, Snowbird, Utah, March 2005 First Place, Predoctoral Basic Science Outstanding Research Award, 2004 American Society of Human Genetics, Toronto Platform Presentation, 2004 American Society of Human Genetics, Toronto 2004 Graduate Fellowship for Outstanding Research Award, University of Florida College of Medicine Lalor Foundation Merit Award for Outstanding Research, 2004 Society for the Study of Reproduction, Vancouver, Canada Lalor Foundation Fellowship, 2004 Society for the Study of Reproduction, Vancouver, Canada Finalist, Trainee Research Award, 2004 Society for the Study of Reproduction, Vancouver, Canada Platform Presentation, 2004 Gordon Conference (Mammalian Gametogenesis and Embryogenesis), CT Scholarship, 2004 Keystone Symposia (Emerging Mechanisms of Epigenetic Regulation), CA Second Place, Predoctoral Basic Science Outstanding Research Award, 2003 American Society of Human Genetics, Los Angeles, CA Platform Presentation, 2003 American Society of Human Genetics, Los Angeles, CA President’s Award for Educational Excellence Honors Program, Kansas Alumni Association Crowell Book Award, University of Kansas McNair Merit Award, University of Kansas Kansas Honor Scholar for Outstanding Academic Achievements |
||
|
Abstracts Presented at Meetings Through Graduate Studies |
||
|
American Society of Human Genetics, Salt Lake City, UT, October 2005, "Epigenetic Regulation of Pericentromeric Heterochromatin during Mammalian Meiosis" (selected for platform presentation) American Society of Human Genetics, Toronto, Canada, October 2004 Society for the Study of Reproduction, Vancouver, Canada, August 2004 Gordon Conference (Mammalian Gametogenesis and Embryogenesis), Connecticut College, June 2004 Keystone Symposia (Emerging Mechanisms of Epigenetic Regulation), Lake Tahoe, CA, January 2004 American Society of Human Genetics, Los Angeles, CA, November 2003 American College of Medical Genetics, San Diego, CA, March 2003 University of Florida College of Medicine Research Day, April 2003 and 2004 Pediatrics Science Day at the University of Florida, 2003 and 2004 University of Florida Graduate & Professional Student Forum, April 2002 and 2003 |
||