Advanced Concentration

Immunology & Microbiology

Mentor

Edward K. L. Chan, Ph.D.

Department

Oral Biology

Enrolled 

August 2004

Lab Room

D5-19

Lab Phone

392-1437

E-mail

kaleb888@ufl.edu

Education

B.S., M.S., Biological Sciences, Marshall University, WV

Dissertation Research

MicroRNA Regulation in GW/P Body Cell Biology, Lipopolysaccharide Signaling, and Rrheumatoid Arthritis

Publications

Jakymiw A, Pauley KM, Li S, Ikeda K, Lian S, Eystathioy T, Satoh M, Fritzler MJ, Chan EK.  The role of GW/P-bodies in RNA processing and silencing. J Cell Sci. 2007 Apr 15;120(Pt 8):1317-23.  abstract

Ikeda K, Satoh M, Pauley KM, Fritzler MJ, Reeves WH, Chan EK.  Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody. J Immunol Methods. 2006 Dec 20;317(1-2):38-44.  abstract

Pauley KM, Eystathioy T, Jakymiw A, Hamel JC, Fritzler MJ, Chan EK.  Formation of GW bodies is a consequence of microRNA genesis. EMBO Rep. 2006 Sep;7(9):904-10.  abstract

Hypes, KM.  Docosahexaenoic acid modulates class I major histocompatibility complex protein function. M.S. Thesis. Marshall University Huntington, WV, 2004.

Abstracts Presented at Meetings

K.M. Pauley, M. Satoh, Y. Li, W. Reeves, and E.K.L. Chan. Effects of innate immune signaling on GW body assembly. Keystone Symposia: MicroRNAs and siRNAs Biological Functions and Mechanisms. Keystone, CO, January 31, 2007.

T. Eystathioy, K.M. Pauley, A. Jakymiw, J.C. Hamel, M.J. Fritzler, and E.K.L. Chan. MicroRNA are critical in GW body formation. Keystone Symposia: RNAi and Related Pathways. Vancouver, Bristish Columbia, January 29, 2006.

T. Eystathioy, K.M. Pauley, A. Jakymiw, J.C. Hamel, M.J. Fritzler, and E.K.L. Chan. MicroRNA are important factors for GW body formation. The American Society for Cell Biology.  45th Annual Meeting. San Francisco, CA, 2005.

T. Eystathioy, K.M. Pauley, A. Jakymiw, J.C. Hamel, M.J. Fritzler, and E.K.L. Chan. GW bodies are cytoplasmic foci committed to micrRNA processing. 9th International Workshop on Autoantibodies and Autoimmunity. Gainesville, FL, September 29, 2005.

Hypes, K.M., Stillwell, W., and Jenski, L. Docosahexaenoic acid modulates class I major histocompatibility complex protein function. 6th Congress of the International Society for the Study of Fatty Acids and Lipids. Brighton, England, June 30, 2004.

Hypes, K. M. and Jenski, L.J. Docosahexaenoic acid affects the binding of b2-microglobulin and monoclonal anti-MHC I antibody to class I MHC molecules. 38th annual Southeastern Regional Lipid Conference, Cashiers, NC, Nov. 13, 2003.

Bush, J. E.., Hypes, K. M., and Jenski, L. J. DHA synergizes with combined TRAIL and chlorambucil in Jurkat and H460 human cancer cells. 38th annual Southeastern Regional Lipid Conference, Cashiers, NC, Nov. 13, 2003.