Pui Y. Lee


Advanced Concentration

Immunology & Microbiology

Mentor

Westley H. Reeves, M.D.

Department

Medicine (Division of Rheumatology & Clinical Immunology)

Enrolled

August 2004

Lab Room

R2-253

Lab Phone

392-9888

E-mail

puilee05@ufl.edu

Education

B.A, Interdisciplinary Studies, University of Florida

Dissertation Research

The role of type-I interferons and toll-like receptors in experimental of systemic lupus erythematosus

Publications

Lee PY, Weinstein JS, Nacionales DC, Scumpia PO, Li Y, Butfiloski E, van Rooijen N, Moldawer L, Satoh M, Reeves WH. A novel type I IFN-producing cell subset in murine lupus. J Immunol. 2008 Apr 1;180(7):5101-8.  abstract

Nacionales DC, Kelly-Scumpia KM, Lee PY, Weinstein JS, Lyons R, Sobel E, Satoh M, Reeves WH. Deficiency of the type I interferon receptor protects mice from experimental lupus. Arthritis Rheum. 2007 Nov;56(11):3770-83.  abstract

Lee PY, Li Y, Richards HB, Chan FS, Zhuang H, Narain S, Butfiloski EJ, Sobel ES, Reeves WH, Segal MS. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus. Arthritis Rheum. 2007 Nov;56(11):3759-69.  abstract

Lee PY, Reeves WH.  Type I interferon as a target of treatment in SLE. Endocr Metab Immune Disord Drug Targets. 2006 Dec;6(4):323-30. Review.  abstract

Zhuang H, Kosboth M, Lee P, Rice A, Driscoll DJ, Zori R, Narain S, Lyons R, Satoh M, Sobel E, Reeves WH.  Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p. Arthritis Rheum. 2006 May;54(5):1573-9.  abstract

Kelly KM, Zhuang H, Nacionales DC, Scumpia PO, Lyons R, Akaogi J, Lee P, Williams B, Yamamoto M, Akira S, Satoh M, Reeves WH.  "Endogenous adjuvant" activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60. Arthritis Rheum. 2006 May;54(5):1557-67.  abstract

Nacionales DC, Kelly KM, Lee PY, Zhuang H, Li Y, Weinstein JS, Sobel E, Kuroda Y, Akaogi J, Satoh M, Reeves WH.  Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane). Am J Pathol. 2006 Apr;168(4):1227-40.  abstract

Lee PY, Scumpia PO, Byars JA, Kelly KM, Zhuang H, Shuster JS, Theriaque DW, Segal MS, Reeves WH, Brantly ML.  Short-term atorvastatin treatment enhances specific antibody production following tetanus toxoid vaccination in healthy volunteers. Vaccine. 2006 May 8;24(19):4035-40.  abstract

Zhuang H, Narain S, Sobel E, Lee PY, Nacionales DC, Kelly KM, Richards HB, Segal M, Stewart C, Satoh M, Reeves WH.  Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus. Clin Immunol. 2005 Dec;117(3):238-50.  abstract

Honors & Awards
2007 First Place, Immunology & Microbiology Advanced Concentration, Medical Guild Graduate Student Research Concentration


Current Students

IDP Students

IDP Home

COM Home

UF Home

last revised 6/16/08  wtm