Advanced Concentration

Biochemistry and Molecular Biology

Mentor

Thomas P. Yang, Ph.D.

Department

Biochemistry & Molecular Biology

Enrolled 

August 2003

Lab Room

R3-273

Lab Phone

846-1636

E-mail

arne@ufl.edu

Education

B.S., Microbiology & Cell Science, University of Florida

Dissertation Research

Structural organization of the Prader-Willi / Angelman syndrome domain

Publications

Baus J, Liu L, Heggestad AD, Sanz S, Fletcher BS. Hyperactive transposase mutants of the Sleeping Beauty transposon. Mol Ther. 2005 Dec;12(6):1148-56.  abstract

Gravenstein K, Heggestad AD, Fortun J, Notterpek L, Pestov DG, Fletcher BS. The WD-repeat protein GRWD1: potential roles in myeloid differentiation and ribosome biogenesis. Genomics. 2005 Jun;85(6):762-73. abstract

Liu L, Sanz S, Heggestad AD, Antharam V, Notterpek L, Fletcher BS. Endothelial targeting of the Sleeping Beauty transposon within lung. Mol Ther. 2004 Jul;10(1):97-105.  abstract

Heggestad AD, Notterpek L, Fletcher BS.  Transposon-based RNAi delivery system for generating knockdown cell lines. Biochem Biophys Res Commun. 2004 Apr 9;316(3):643-50.  abstract

Abstracts Presented at Meetings

Heggestad, AD; TR Dennis; S Rodriguez-Jato; BA Gray; RT Zori; DJ Driscoll; TP Yang. (2005) Spatial organization of the Prader-Willi/Angelman syndrome locus is dependent on the parent of origin. American Society for Human Genetics 55th Annual Meeting, Salt Lake City, UT.

Rodriguez-Jato, S; J Shan; SH Kang; JO Brant; AD Heggestad; TP Yang. (2005) Deletion of the endogenous HPRT promoter on the active X chromosome leads to complex alterations of histone modification patterns. American Society for Human Genetics 55th Annual Meeting, Salt Lake City, UT. (Poster)

Honors & Awards

American Society of Human Genetics, Predoctoral Presentation Award Finalist, 55th Annual Meeting, Salt Lake City, UT, October 2005