|
Brittney L. Gurda |
|
|
|
Advanced Concentration |
Biochemistry and Molecular Biology | |
|
Mentor |
Mavis Agbandje-McKenna, Ph.D. | ||
|
Department |
Biochemistry & Molecular Biology | ||
|
Enrolled |
August 2005 | ||
|
Lab Room |
LG-171 | ||
|
Lab Phone |
846-2001 | ||
|
|
bgurda@ufl.edu | ||
|
Education |
|||
|
B.S., Microbiology & Cell Science, University of Florida |
|||
|
Dissertation Research |
|||
| Mapping Dominant Antigenic Regions on Adeno-Associated Virus Capsids | |||
|
Publications |
|||
Matthew Mitchell, Hyun-Joo Nam, Adam Carter, Angela McCall, Chelsea Rence, Antonette Bennett, Brittney Gurda, Robert McKenna, Mark Porter, Yoshihisa Sakai, Barry J. Byrne, Nicholas Muzyczka, George Aslanidi,Sergei Zolotukhin and Mavis Agbandje-McKenna. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9. Acta Crystallographic Sect F Struct Biol Cryst Commun. 2009 July;65 (Pt 7): 715-718. abstract |
|||
|
Quesada O, Gurda B, Govindasamy L, McKenna R, Kohlbrenner E, Aslanidi G, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1073-6. abstract |
|||
|
Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structure of Adeno-Associated virus serotype 8, a gene therapy vector. J Virol. 2007 Aug 29; [Epub ahead of print] abstract |
|||
|
Grieger JC, Johnson JS, Gurda-Whitaker B, Agbandje-McKenna M, Samulski RJ. Surface exposed Adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of non-infectious wild-type Vp2/Vp3 and Vp3-only capsids, but not 5-fold pore mutant virions. J Virol. 2007 Aug;81(15):7833-43. abstract |
|||
|
Miller EB, Gurda-Whitaker B, Govindasamy L, McKenna R, Zolotukhin S, Muzyczka N, Agbandje-McKenna M. Related Articles, Links Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1271-4. abstract |
|||
|
Nam HJ, Gurda-Whitaker B, Gan WY, Ilaria S, McKenna R, Mehta P, Alvarez RA, Agbandje-McKenna M. Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation. J Biol Chem. 2006 Sep 1;281(35):25670-7. abstract |
|||
|
DiMattia M, Govindasamy L, Levy HC, Gurda-Whitaker B, Kalina A, Kohlbrenner E, Chiorini JA, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt 10):917-21. abstract |
|||
|
Lane MD, Nam HJ, Padron E, Gurda-Whitaker B, Kohlbrenner E, Aslanidi G, Byrne B, McKenna R, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt 6):558-61. abstract |
|||
| Abstracts Presented at Meetings | |||
12th Annual Meeting of the American Society of Gene Therapy, 2009. San Diego, California. Towards Characterizing Vector-Host Interactions: Adeno-Associated Virus Capsids in Complex with Antibody Fragments. Brittney L. Gurda, Michael DiMattia, Edward B. Miller, Anita Patel, Antonette Bennett, Robert McKenna, Sergei Zolotukhin, Weijun Chen, Nick Muzyczka, Wendy Weichert, Christian Nelson, Jay Chiorini, Norm Olson, Tim S. Baker, Colin R. Parrish, and Mavis Agbandje-McKenna. |
|||
|
XIIth Parvovirus Workshop 2008, Cordoba, Spain. STRUCTURAL STUDIES OF BOCAVIRUSES: INSIGHTS INTO THE STRUCTURAL REPERTOIRE OF THE PARVOVORIDAE. Brittney L. Gurda, Heather Bladek, Alejandro Castro, Lakshamanan Govindasamy, Robert McKenna, Norm Olson, Robert Sinkovits, Tim S. Baker, Kevin Brown, Mavis Agbandje-McKenna. |
|||
|
XIIth Parvovirus Workshop 2008, Cordoba, Spain. STUDIES TOWARDS ENGINEERING IMMUNOEVASIVE AAV CAPSIDS FOR IMPROVED GENE THERAPY APPLICATIONS. Brittney L. Gurda, Michael DiMattia, Edward B. |
|||
|
XXth Biennial Conference on Phage/Virus Assembly 2007. Barrie, Ontario, Canada. Mapping Dominant Antigenic regions on Adeno-Associated Virus Capsids. Brittney L. Gurda, Edward Miller, Michael DiMattia, Robert McKenna, Wendy Weichert, Christian Nelson, Colin R. Parrish, Sergei Zolotukhin, Michael Schmidt, Jay Chiorini, Norm Olson, Tim Baker, Mavis Agbandje-McKenna. |
|||
| 2007 Annual Meeting of the American Society for Virology. Corvallis, Oregon. Mapping Dominant Antigenic regions on Adeno-Associated Virus Capsids. Brittney L. Gurda, Edward Miller, Michael DiMattia, Robert McKenna, Wendy Weichert, Christian Nelson, Colin R. Parrish, Sergei Zolotukhin, Michael Schmidt, Jay Chiorini, Norm Olson, Tim Baker, Mavis Agbandje-McKenna. |
|||
| XIth Parvovirus Workshop 2006, Les Diablerets, Switzerland. Mapping the Antigenic Site(s) of Neutralizing Antibodies on the Capsid of Adeno-Associated Virions. Brittney L. Gurda-Whitaker, Edward Miller, Michael DiMattia, Colin R. Parrish, Sergei Zolotukhin, Jay Chiorini, Robert McKenna, Mavis Agbandje-McKenna. |
|||
| Honors & Awards | |||
American Society of Gene Therapy travel grant for the 2009 meeting in San Diego, California |
|||
| Bronze Medal, 2009 Medical Guild Graduate Student Research Competition | |||
| First Place, 2009 Biochemistry & Molecular Biology Medical Guild Graduate Student Research Competition | |||
| Howard Hughes Medical Institute Graduate Student Award, 2006 | |||
last revised 7/7/09 tr