College of Medicine Research Seminar Schedule

Fall 2002 - Spring 2003

Thursdays at 4:00 PM in Room C1-15

FALL 2002

DATE SPEAKER SEMINAR TITLE

August 29

Seong Jin Kim, Ph.D., Lab. of Cell Regulation & Carcinogenesis, NIH (hosted by Dr. Paul Oh)

Mechanism of Inactivation of TGF-beta Signaling During Carcinogenesis:  Inactivation of Smads

September 5 Michal Jazwinski, Ph.D., Biochemistry & Molecular Biology, Louisiana State Univ. (hosted by Dr. John Aris) Mitochondria and Aging:  Why Children Are Born Young
September 12 Barry Rosen, Ph.D., Biochemistry & Molecular Biology, Wayne State Univ. School of Medicine (hosted by Dr. Brian Cain) Structure of Arsenic Detoxification Enzymes
September 19 Bryce Paschal, Ph.D., Biochemistry & Molecular Genetics, Univ. Virginia (hosted by Dr. Carl Feldherr) Pathways of RNA and Protein Export from the Nucleus
September 26 Kevin K.W. Wang, Ph.D., Psychiatry & Neuroscience, McKnight Brian Inst., Univ. Florida (hosted by Dr. Ron Hayes) Protease Overactivation in CNS Injury:  Insight into Disease Mechanisms and Biomarker Opportunities
October 3 Stephen Baylin, M.D., Cellular & Molecular Medicine, Johns Hopkins Univ. (hosted by Dr. Lei Xiao)               Aberrant Gene Silencing in Cancer:  The Chromatin Connection
October 10 Joseph R. Vasselli, Ph.D., Obesity Research Center, Columbia Univ. (hosted by Dr. Philip Scarpace) The Role of Leptin in the Regulation of Body Weight:  A Reappraisal
October 24 Shalesh Kaushal, M.D., Ph.D., Ophthalmology, Univ. Florida (hosted by Dr. Al Lewin) Molecular and Cellular Consequences of Misfolded Rhodopsin Mutants Associated with Autosomal Dominant Retinitis Pigmentosa (ADRP)
October 31 Peter A. Rubenstein, Ph.D., Biochemistry, Univ. Iowa (hosted by Dr. Michael Bubb) Yeast Actin:  A Functionally Informative Actin Isoform
November 7 Brenda L. Bass, Ph.D., Biochemistry, Univ. Utah, HHMI (hosted by Dr. Maury Swanson) Cellular Functions of Double-Stranded RNA:  RNA Editing & RNA Interference
November 14 Graham Warren, Ph.D., Cell Biology, Yale Univ. School of Medicine (hosted by Dr. Brian Burke) Biogenesis of the Golgi Apparatus
November 21 Dorothee Kern, Ph.D., Biochemistry, Brandeis Univ. (hosted by Dr. Art Edison) Enzymes in Action in the NMR Tube: Protein Dynamics During Catalysis and Signaling
December 5 Paul Friesen, Ph.D., Biochemistry, Inst. Molecular Virology, Univ. Wisconsin (hosted by Dr. Richard Moyer) Regulation of Apoptosis:  New Lessons from the Baculoviruses
 
SPRING 2003
DATE SPEAKER SEMINAR TITLE
January 9 Hermann Steller, Ph.D., HHMI, Rockefeller Univ. (hosted by Dr. Lei Zhou) Death by Design:  Mechanism & Regulation of Apoptosis
January 16 Monica Driscoll, Ph.D., Rutgers Univ. (hosted by Dr. Art Edison) How to Feel:  Molecular Mechanisms of Touch Sensation in C. elegans
January 23 Charles Thornton, M.D., Univ. Rochester (hosted by Dr. Maurice Swanson) RNA-Mediated Diseases
January 30 Peggy Hsieh, Ph.D., NIH (hosted by Dr. Linda Bloom) Safeguarding the Genome: Molecular Mechanisms of DNA Mismatch Repair
February 6 D. Wade Clapp, M.D., Indiana Univ. (hosted by Dr. Joyce Koenig) Implications of Ras-Rac-Pak Signaling Pathway in the Pathogenesis of Neurofibroma Formation in Individuals with Neurofibromatosis Type 1
February 13 Derek van der Kooy, Ph.D., Univ. Toronto (hosted by Dr. Nao Terada) How to Make a Mammalian Brain
February 27 Billy W. Day, Ph.D., Univ. Pittsburgh (hosted by Dr. Bryon Petersen) Cancer Drug Discovery Through Combinatorial Chemistry, High Throughput Screening & High Content Cell Profiling
March 6 Robert E. Johnston, Ph.D., Univ. North Carolina (hosted by Dr. Sue Moyer) Alphavirus Replicon Vaccines for Immunodeficiency Viruses
March 13 Bernard Moss, M.D., Ph.D., NIH (hosted by Dr. Rich Condit) Assembly and Intracellular Movement of Vaccinia Virus
March 20 Elliott D. Kieff, M.D., Ph.D., Harvard Univ. (hosted by Dr. Sankar Swaminathan) Efficient Immortality & Lymphoma - Epstein-Barr Virus & Human Lymphocytes
March 27 Victor R. Ambros, Ph.D., Dartmouth Univ. (hosted by Dr. Bert Flanegan) Small RNAs and Developmental Timing in Animals
April 3 John F. Engelhardt, Ph.D., Univ. Iowa (hosted by Dr. Terry Flotte) Redox-Modulating Gene Therapies for Environmentally Induced Liver Injuries
Friday, April 11
8:30-11:00 am
HPNP Auditorium
COM Research Day - Medical Guild Research Competition
Christopher Williams, Biochemistry & Molecular Biology A Tale of Two States:  The ATP-dependent Conformational Change in the Escherichia coli DNA Polymerase III Clamp Loader
Stormy Chamberlain, Genetics  Dissecting the Phenotype of Prader-Willi Syndrome Mice
Jin He, Immunology & Microbiology Discovery and Functional Study of Novel Tumor Specific Genes for Cancer Gene Therapy
Steve Guthrie, Molecular Cell Biology Role of ENOS and INOS in Hemangbioblast Activity and Blood Vessel Formation
Erin Keen Rhinehart, Neuroscience  Leptin Receptor Replacement in the Brain using Adeno-Associated Viral Vectors
Jared T. Wilsey, Physiology & Pharmacology Doxycycline-Inducible Leptin Gene Therapy:  Reversible Transgene Expression and Physiological Responses
11:00-12:00
HPNP Auditorium
Medical Student Research Presentations
12:00-1:00
12:00-2:30
Lunch & Medical Guild Awards
Research Posters
HPNP Reception Area
2:30-3:30
HPNP Auditorium

Terence R. Flotte, M.D., COM Faculty Clinical Science 2002 Awardee
Pushpa S. Kalra, Ph.D., COM Faculty Basic Science 2002 Awardee

Development of Gene Therapies for Cystic Fibrosis and Alpha-1 antitrypsin Deficiency
Why Be Fat?

3:30-4:30
HPNP Auditorium

Health Science Center Research Week Keynote SpeakerPeter M. Small, M.D., Associate Professor, Medicine, Stanford University Medical Center;  Program Officer, HIV/AIDS & TB, Global Health Program, Bill and Melinda Gates Foundation

Tuberculosis: The Intersection of Basic Science and Public Health
April 24 Kevin P. Campbell, Ph.D., HHMI, Univ. Iowa (hosted by Dr. Barry Byrne) New Insights into the Pathogenesis & Treatment of Muscular Dystrophy
TBA Mark Pittenger, Ph.D., Osiris (hosted by Dr. Ed Scott) TBA

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4-21-04  WTM