GMS 6005 - Spring 2009       

Fundamentals of Developmental Biology
 
Course Director:  Paul Oh, Ph.D.
Lectures:  Mondays, Wednesdays, Fridays at 8:30-9:20 and 9:35-10:25 (G110 (HPNP); http://www.phhp.ufl.edu/tools/hpnp/0212-G.pdf )
Discussions:  Tuesdays and/or Thursdays at 8:30-9:30am (G110 HPNP)
 RCR (GMS7003); Thursdays 4:00 -5:00 LG101A; Tuesdays TBL 3:30 (G103 HPNP)
Reviews & Exams

Suggested Reading:  The lecturer will provide review articles pertinent to each lecture  (check the "course documents" in the ModCore)

Shown below is a table displaying the tentative dates, titles and instructors for all of the lectures and discussions for Spring 2009.   For course content, registered students should log-in to the core course site at ModCore. 
   
Day Date Room Lecture Title Faculty
L1 Mon 3/22 G110

Introduction / Diverse methods & species used in developmental studies.

B. Harfe
L2 Mon 3/22 G110 Genetic approaches in mammalian development. B. Harfe
L3 Wed 3/24 G110 Drosophila – AP patterning L. Zhou
L4 Wed 3/24 G110 Drosophila – DV patterning L. Zhou
D1 Thu 3/25 G110

Journal Discussion (1): Andrioli, LPM (2002) Anterior repression of a Drosophila stripe enhancer requires three positionspecific mechinism. Development  129:4931-2940

 L. Zhou
RCR Thu 3/25 LG101A GMS7003  
L3 Fri 3/26  G110 Midblastula transition (switch from maternal to fetal control) J. Resnick
L4 Fri 3/26 G110 Gastrulation / (Mesoderm Induction & Organizer) J. Resnick
L5 Mon 3/29 G110

Germ cell differentiation

 J. Resnick
L6 Mon 3/29 G110 Urogenital Development/Sex differentiation J. Resnick
D2 Tue 3/30 G110

Journal Discussion (2):

Belaoussoff, M.et al (1998).Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development 125:5009-5018.

 J. Resnick
RCR Tues 3/30 G103 HPNP GMS7003 TBL  
L7 Wed 3/31 G110 Limb patterning I B. Harfe
L8 Wed 3/31 G110 Limb patterning II B. Harfe
D3 Thu 4/1 G110

Journal Discussion (3)

Cretekos, CJ(2008) Regulatory divergence modifies limb length between mammals, Geenes Dev 22:141-151

 S. Paul Oh
S Thu 4/1 LG101A GMS7003
L9 Fri 4/2 G110 Muscle Development (I) M. Swanson
L10 Fri 4/2 G110 Muscle Development  Development (II) M. Swanson
L11 Mon 4/5 G110 Hematopoiesis and Leukemia L. Wu
  Tue 4/6 G110 Journal Discussion (4) L. Wu
  Tue 4/6 G110

Exam 1

  
L12 Wed 4/7 G110 Zdbrzfish as a model system for studying Neural Development K. Epley
D5 Thu 4/8 G110

Journal Discussion (5)

McLean DL et al (2007) A topographic map of recruitment in spinal cord.  Nature 446: 71-5

  
S Thu 4/8 LG101A GMS7003
 
L13 Fri 4/9 G110 Stem Cells in Development and Homeostasis Regeneration and Regenerative Medicine. N. Terada
 
L14 Mon 4/12 G110 Left-Right Asymmetry S. Paul Oh
          S. Paul Oh
D6 Tue 4/13 G110

Journal Discussion (6)

Nakamura, T. et al (2006) Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system. Dev. Cell  11, 495-504.

 S. Paul Oh
RCR Tues 4/13 G103 HPNP GMS7003 TBL  
L15 Wed 4/14 G110 External Genitalia Development M. Cohn
L16 Wed 4/14 G110 Evolution of developmental mechanisms M. Cohn
D7 Thu 4/15 G110

Journal Discussion (7)

Tarchini, B.  et al., 2006. Control of Hoxd Genes' collinearity during early limb Development Dev. Cell 10, 93-103.

 M. Cohn
S Thu 4/15 LG101A GMS7003
L17 Fri 4/16 G110

Cardiac Development (I)

Cardiac Development (II)

 H. Kasahara
L18 Mon 4/19 G110

Vascular Development:  Vaseculogenesis and Angiogenesis

Vascular Developm ent:  Arteriogenesis and Remodleing

 S.P. Oh
D8 Tue 4/20 G110

Journal Discussion (8)

Hellstrom, M. et al (2007) D114 signaling through Notch 1 regulates formation of tip cells during angiogenesis.  Nature 445:776.

L. Wu
Wed 4/21 G110 Exam (8:30-10:30)  
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