GMS 6005 - Spring 2008Fundamentals of Developmental Biology |
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| Course Director: Paul Oh, Ph.D. | |||||
| Lectures:
Mondays,
Wednesdays, Fridays at 8:30-9:20 and 9:35-10:25 (LG 110A; McKnight Brain
Institute) Discussions: Tuesdays and/or Thursdays at 8:30-9:30am (LG 110A; McKnight Brain Institute) Seminar: Thursdays at 4:00-5:00 (LG101A) Reviews & Exams Suggested Reading: The lecturer will provide review articles pertinent to each lecture (check the "course documents" in the Web CT) Shown below is a table displaying the tentative dates, titles and instructors for all of the lectures and discussions for Spring 2008. For course content, registered students should log-in to the core course site at Web CT Vista. |
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| Day | Date | Room | Lecture Title | Faculty | |
| L1 | Mon | 3/24 | LG 110A |
Introduction / Diverse methods & species used in developmental studies. |
B. Harfe |
| L2 | Mon | 3/24 | LG 110A | Genetic approaches in mammalian development. | |
| L3 | Wed | 3/26 | LG 110A | Drosophila – AP patterning | L. Zhou |
| L4 | Wed | 3/26 | LG 110A | Drosophila – DV patterning | L. Zhou |
| D1 | Thu | 3/27 | LG 110A |
Journal Discussion (1):Nusslein-Volhard and Wieschaus (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287, 795. |
L. Zhou |
| S | Thu | 3/27 | LG101A | IDP Seminar | |
| L3 | Fri | 3/28 | LG 110A | Midblastula transition (switch from maternal to fetal control) | J. Resnick |
| L4 | Fri | 3/28 | LG 110A | Gastrulation / (Mesoderm Induction & Organizer) | J. Resnick |
| L5 | Mon | 3/31 | LG 110A |
Germ cell differentiation |
J. Resnick |
| L6 | Mon | 3/31 | LG 110A | Urogenital Development/Sex differentiation | J. Resnick |
| D2 | Tue | 4/1 | LG 110A |
Journal Discussion (2): Belaoussoff, M., Farrington, S.M., and Baron, M.H. 1998. Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling and the mouse embryo. Development 125:5009-5018. |
J. Resnick |
| L7 | Wed | 4/2 | LG 110A | Left-Right Asymmetry | S. Paul Oh |
| L8 | Wed | 4/2 | LG 110A | Neural Induction | S. Paul Oh |
| D3 | Thu | 4/3 | LG 110A |
Journal Discussion (3) McGrath, J., et al., 2003 Two Populations of Node Monocilia Initiate Left-Right Asymmetry in Mouse. Cell, 114, 61-73. |
S. Paul Oh |
| S | Thu | 4/3 | LG101A | IDP Seminar | |
| L9 | Fri | 4/4 | LG 110A | Cardiac Development (I) | H.Kasahara |
| L10 | Fri | 4/4 | LG 110A | Cardiac Development (II) | H. Kasahara |
| L11 | Mon | 4/7 | LG 110AA | Limb patterning (I) | B. Harfe |
| L12 | Mon | 4/7 | LG 110A | Limb patterning (II) | B. Harfe |
| Tue | 4/8 | LG 110A |
Exam 1 |
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| Wed | 4/9 | LG 110A | Zdbrzfish as a model system for studying Neural Development | K. Epley | |
| D5 | Thu | 4/10 | LG 110A | Journal Discussion (5) | |
| S | Thu | 4/10 | LG101A | IDP Seminar | |
| L13 | Fri | 4/11 | LG 110A | Muscle Development (I) | M.Swanson |
| L14 | Fri | 4/11 | LG 110A | Muscle Development (II) | M.Swanson |
| L17 | Mon | 4/14 | LG 110A | Somitogenesis and Vertebral Patterning: Vascular Develepment | S. Paul Oh |
| L18 | Mon | 4/14 | LG 110A | Vascular Development | S. Paul Oh |
| D6 | Tue | 4/15 | LG 110A |
Journal Discussion (6) Zhong, T.P., Childs, S., Leu, J.P., and Fishman, M.C. 2001 Gridlock signalling pathway fashions the first embryonic artery. Nature 414:216-220. |
S. Paul Oh |
| L19 | Wed | 4/16 | LG 110A | External Genitalia Development | M. Cohn |
| L20 | Wed | 4/16 | LG 110A | Evolution of developmental mechanisms | M. Cohn |
| D7 | Thu | 4/17 | LG 110A |
Journal Discussion (7) Tarchini, B. et al., 2006. Control of Hoxd Genes' Collinearity during Early Limb Development Dev. Cell 10, 93-103. |
M. Cohn |
| S | Thu | 4/17 | LG 110A | IDP Seminar | |
| L21 | Fri | 4/18 | LG 110AA | Stem Cells in Development and Homeostasis Regeration and Regenerative Medicine | N. Terada |
| L23 | Mon | 4/21 | LG 110AA | Hematopoiesis and Leukemia | L. Wu |
| D8 | Tue | 4/22 | LG 110A |
Journal Discussion (8) Calvi, L.M. et al., 2003. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425. 841-846 |
L. Wu |
| Wed | 4/23 | LG 110A | Exam (8:30-10:30) | ||
3/13/08 sg