Eugene P. Goldberg, Ph.D.
Genzyme Professor of Biomaterials
Materials Science & Engineering
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Eugene P. Goldberg, Ph.D. |
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Intratumoral Chemotherapy/Clinical Oncology Research on this novel approach to localized chemotherapy has been pioneered at UF beginning about 25 years ago, initially with NIH. Intratumoral (IT) injections of drug-loaded albumin and DNA mesospheres (1-10 microns) have been very effective in preclinical lung and breast cancer studies. Direct bronchoscopic IT drug injections in lung cancer patients is being done in collaboration with Dr. S. Celikoglu in Istanbul, Turkey at the Nightingale Hospital. Results to date are remarkable with almost immediate relief of airways obstruction and no systemic toxicity.
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Status: Inquire About New Students This Year Contact Information: office: MAE 317 lab: MAE phone: 392-4907 email: egold@mse.ufl.edu Home Page Biography: Dr. Goldberg is the Genzyme Professor for Biomaterials, Materials Science and Engineering, Adjunct Professor of Pharmacology and Therapeutics, and is a member of the faculty of the Biomedical Engineering Dept. and the Chemistry Dept. He has made a number of research contributions in the fields of Biomedical Materials, Implants, Devices, Wound Healing, CNS Repair, and Localized Cancer Chemotherapy. His research group has conducted pioneering studies in the specific fields (1) surface modified ocular implants, (2) tissue-protective polymer coatings to prevent tissue damage during surgery, (3) nano/meso/microspheres for localized drug delivery and intratumoral cancer chemotherapy and immunotherapy, and (4) nanostructured biopolymer scaffolds and gels for nerve tissue regeneration and spinal cord repair. A number of patented medical technologies have emerged from this work and have been licensed by UF for development and clinical use. Dr. GoldbergÕs achievements has been the recipient of the 1998 Biomaterials Society Clemson Award for Applied Research, the Genzyme Corp. Biomaterials Professorship in MSE in 1999, and the 1995 Brown University Distinguished Alumnus Award. He was elected a Fellow of the American Institute for Medical and Biological Engineering in in 2001 and a Fellow of the International Society for Biomaterials in 2008. He is the senior author of more than 415 peer reviewed publications, papers, book chapters, edited books, and invited lectures. |
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